Can't print large documents.

For years, we've been printing large documents to our plotter without issue.  Suddenly last week, nothing large will print.

I've seen a few different error messages, and have tried different computers, and different versions of Illustrator, but nothing large will print.

When trying to print, I currently get the following:

I've also seen an error suggesting not enough memory is available, which is bogus.  And I think another error that was more vague, something to the effect of "can't print"

I've setup a clean install of illustrator on a clean windows install, same issue.

I setup an alternate print server with our rip software, same software we've been using for years.  Same error on the alternate server.

Nothing changed, and it's effecting everything here, and new installs.  I don't know what happened, but this is getting critical, we need the ability to print.